Accurate and precise measurement of pharmaceutical drugs in complex matrices can be challenging due to the presence of matrix contaminants. To ensure the highest levels of accuracy and precision, it is imperative to use highly robust analytical techniques. Triple quadrupole mass spectrometers are widely used in quantitative bioanalysis because of their stable analytical performance over an extended period. Here, exceptional sensitivity and stability were demonstrated to support bioanalytical workflows in high-throughput laboratories.

The liver is the most common metastatic site for many primary tumors. Single-cell gene and protein expression, in combination with spatial data that contextualizes relationships with other tumor cells and structures, are critical to fully understand how cells communicate in liver metastases.
Resolving the precise spatial location of each single cell allows for a comprehensive understanding of the tissue architecture for each tumor and helps identify critical cell–cell communication circuits.
This webinar will highlight approaches to generating a spatial atlas of tumors, illustrate how to integrate single-cell transcriptomics data with spatial data and explore how to track cell behavior to study cell–cell interactions in each cellular neighborhood.

In this webinar, you’ll hear from Christof Lenz, PhD, about the importance of analyzing tissue samples in biomedical proteomics, particularly for understanding the molecular basis of cardiac diseases. Our second speaker, Greg Potts, PhD, will showcase how chemoproteomics, in combination with data-independent acquisition, speeds up drug discovery.

In this exclusive extended webinar, immerse yourself in a world of innovation as our expert speakers unveil state-of-the-art systems and workflows designed to optimize screening assays with unparalleled throughput and reproducibility.

Biotherapeutic drugs are complex and can perform their function through interactions with more than one target molecule. During development and quality control, a range of analytical technologies are used to characterize biotherapeutic drugs in terms of their structural integrity and activity. Ligand-binding assays are relevant for characterization and quantitation of the functional drug, however current analytical approaches may no longer be sufficient for analysis of emerging drug modalities.
Biacore™ assays are based on ligand binding and used in development and characterization of drug product using active concentration measurements, target binding, potency (E50)
and Fc receptor (FcR) analysis.

High concentrations of human lactoferrin (hLF) in human milk offer health benefits for infants and adults, including nourishment and growth support.
Recombinant hLF (rhLF) has been expressed in yeast at an industrial scale, with the aim of making it affordable and accessible as a supplement.
This webinar takes a deep dive into how rhLF can be characterized and analyzed to ensure its safety for consumption in clinical studies.
Our expert speaker will cover how various analytical techniques – including microfluidic modulation spectroscopy – can confirm identity, assess purity and impurities, measure size and investigate the structure of rhLF, as well as compare it to native hLF.