Label-Free Protein Activity Quantification for Drug Production and QC
Biotherapeutic drugs are complex and can perform their function through interactions with more than one target molecule. During development and quality control, a range of analytical technologies are used to characterize biotherapeutic drugs in terms of their structural integrity and activity. Ligand-binding assays are used for both characterization and quantitation of biotherapeutic drugs, however, current analytical approaches may no longer be sufficient for analyzing emerging drug modalities.
In this webinar, you will hear how label-free, ligand-binding-based assays can be used throughout the development and manufacturing of drug products for active concentration measurements, target binding, potency (E50) and Fc receptor (FcR) analysis.
Attend this webinar to discover label-free assays for:
- The quantitation of therapeutic proteins from plasma fractionation
- Titer analysis of adeno-associated virus
- Assessing drug potency based on ligand binding