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Latest App Notes & Case Studies

Purple and blue background with falling transparent particles in the foreground
App Note / Case Study

A Powerful Tool for Bioanalysis in Complex Matrices

This app note highlights a system that can minimize downstream ion path contamination, maintaining the highest levels of sensitivity and stability over an extended period.
Cancer cells under a microscope, showing abnormal growth and division.
App Note / Case Study

A Rapid and Robust Solution for Cellular Response Characterization

This app note explores the use of an assay to facilitate rapid monitoring of T-cell function and simultaneous assessment of cell phenotype, activation markers, proliferation, viability and cytokine secretion.
Liver Fibrosis
App Note / Case Study

A Novel Approach for Non-Invasive Liver Research

This case study utilizes non-invasive ultrasound imaging to visualize and quantify liver echogenicity and stiffness, providing critical insights into both disease progression and the efficacy of therapeutic interventions in mouse models.
Assessing the Functionality of PBMCs After Cryopreservation
App Note / Case Study

Assessing the Functionality of PBMCs After Cryopreservation

As PBMCs continue to see an increase in use in the testing of new biological therapeutic compounds, ensuring purified cells retain functionality after cryopreservation is critical.
engineered stable mAbs
App Note / Case Study

Biologics Developability: Optimization of Engineered mAbs With Multi-Parameter Stability Characterization

The biologic drug development process is expensive and often leads to time and money lost on candidates that never reach the clinic. Improved developability profiles enable researchers in the early discovery stages to select candidates that have a great chance at clinical success.
Neuro Research
App Note / Case Study

Speeding Up Neuroscience Research

Delve into this case study to explore how a research lab at King’s College London used hiPSC-derived neurons to shed light on synaptic biology and potential treatments for psychiatric conditions.
Neuro Program
App Note / Case Study

Precision Reprogrammed iPSC Models for High-Throughput Drug Discovery

This app note delves into the role of TDP-43 protein aggregates in the disease's progression. Charles River Laboratories and bit.bio present a breakthrough in ALS research with genetically matched ioGlutamatergic Neurons, providing a crucial in vitro model.
AKTA System
App Note / Case Study

Single-Use Technology Designed for Small Batches in Gene Therapy Manufacturing

But how do you purify small volumes for preclinical and clinical studies without losing too much to processing or leaving capacity unused?
High Throughput Bulk RNA Barcoding and Sequencing
App Note / Case Study

High-Throughput Bulk RNA Barcoding and Sequencing

This app note highlights a convenient, efficient and reliable workflow for massively multiplexed RNA-seq experiments.
Vaccine Vials
App Note / Case Study

Viral Clearance in a Downstream AAV Process

This application note shows how chromatographic modes of separation can achieve the necessary levels of virus removal while preserving the integrity of the AAV product.
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