Organ-on-Chips Revolutionize Drug Safety Testing
Both animal and in vitro 2D cell culture models used during preclinical trials cannot faithfully replicate the physiological conditions of human in vivo cellular environments. As a result, over 90% of new compounds fall short during clinical trials.
Organ-on-chip (OOC) models have emerged as a way to replicate the complex microenvironment of human organs in vitro, allowing researchers to test drugs and study diverse physiological processes.
This whitepaper explores the latest advancements in OOC platforms that can help to efficiently simulate drug toxicity responses.
Download this whitepaper to discover:
- Liver- and kidney-on-chip models for simulating toxicity responses
- High-content imaging to visualize cell interactions, structures and responses
- How OOC models can reduce development costs and improve success rates