Recent Advances in Screening Technologies for Human Monoclonal Antibodies for Infectious Diseases

Dr. Crowe is Director of the Vanderbilt Vaccine Center and the Ann Scott Carell Professor of Pediatrics, Pathology, Microbiology, and Immunology at Vanderbilt University Medical Center. He is a board-certified pediatric infectious diseases physician and viral immunology researcher. His laboratory studies the human immune response to infection for a wide variety of major human pathogens, including many emerging infections. He is an elected member of the National Academy of Medicine and National Academy of Inventors, is an ISI Highly Cited Researcher and has been the recipient of numerous investigator awards. Recent Advances in Screening Technologies for Human Monoclonal Antibodies for Infectious Diseases Human monoclonal antibodies are increasingly being used to prevent or treat infectious diseases. The list of key features needed to identify promising leads that can be developed as biological drugs is evolving rapidly. In this webinar, Dr. James E. Crowe from Vanderbilt University Medical Center will discuss current approaches to screening for high potency, broad reactivity, synergistic combinations and reduced escapability. Attendees will gain insights into: • Cutting-edge screening strategies for pinpointing high potency antibodies • Exploring the landscape of broadly reactive antibodies through current methodologies • Unraveling the potential of synergistic combinations of antiviral antibodies • Navigating the challenge of reducing escapability in neutralizing antibodies