Latest App Notes & Case Studies

This app note highlights the use of electron-activated dissociation and collision-induced dissociation to enhance the fragmentation of peptides from casein tryptic digests.

This application note describes how capillary gel electrophoresis with UV detection (CGE-UV) can attain single-nucleotide resolution over a broad size range, making it suitable for the development of QC assays.

This application note presents a case study where a manual cloning approach was adapted with an automated platform to expedite experiments on 96-well and 384-well plates.

This app note highlights an assay that enables streamlined, sensitive detection and characterization of mitochondrial toxicants.

This application note presents a highly sensitive signature peptide quantification workflow using cutting-edge accurate mass spectrometry technology.

This application note demonstrates how timsTOF and single-cell proteomics (SCP) approaches can be combined to create a robust and sensitive immunopeptidomics workflow.

This app note highlights how a handheld electronic pipette can help researchers save time and increase homogeneous crystal growth.

QC can be performed after data acquisition, but unexpected deviations can waste valuable time and resources. Instead, real-time QC allows for active monitoring of data quality as the analysis is being performed, preventing errors that can compromise the analysis.

Oligonucleotides play a crucial role in modern drug development, therefore their accurate characterization is essential. However, given the sheer complexity and diversity of the types of oligonucleotides that are in clinical development, a range of diverse analytical approaches are necessary.

Mass spectrometry is regarded as the gold standard for protein identification; however, this technique cannot easily discriminate between protein variants and is not accessible to everyday scientists due to the high cost, space and expertise required.