Latest App Notes & Case Studies
App Note / Case Study
Improving Complex Phosphopeptide Characterization
This app note highlights the use of electron-activated dissociation and collision-induced dissociation to enhance the fragmentation of peptides from casein tryptic digests.
App Note / Case Study
High-Resolution mRNA Poly(A) Tail Analysis With CGE-UV
This application note describes how capillary gel electrophoresis with UV detection (CGE-UV) can attain single-nucleotide resolution over a broad size range, making it suitable for the development of QC assays.
App Note / Case Study
Automate Assembly Cloning Using a Liquid Handling Platform
This application note presents a case study where a manual cloning approach was adapted with an automated platform to expedite experiments on 96-well and 384-well plates.
App Note / Case Study
Streamlined Detection and Characterization of Mitochondrial Toxicants
This app note highlights an assay that enables streamlined, sensitive detection and characterization of mitochondrial toxicants.
App Note / Case Study
Sensitive Signature Peptide Quantification Using Accurate Mass Spectrometry
This application note presents a highly sensitive signature peptide quantification workflow using cutting-edge accurate mass spectrometry technology.
App Note / Case Study
High Sensitivity Immunopeptidomics Using Mass Spectrometry
This application note demonstrates how timsTOF and single-cell proteomics (SCP) approaches can be combined to create a robust and sensitive immunopeptidomics workflow.
App Note / Case Study
Easy Set-Up for Protein Crystallization Experiments
This app note highlights how a handheld electronic pipette can help researchers save time and increase homogeneous crystal growth.
App Note / Case Study
Real-Time Quality Control Software for Metabolic Phenotyping
QC can be performed after data acquisition, but unexpected deviations can waste valuable time and resources. Instead, real-time QC allows for active monitoring of data quality as the analysis is being performed, preventing errors that can compromise the analysis.
App Note / Case Study
Oligonucleotide Purity Analysis With Side-Product Identification and Quantitation
Oligonucleotides play a crucial role in modern drug development, therefore their accurate characterization is essential. However, given the sheer complexity and diversity of the types of oligonucleotides that are in clinical development, a range of diverse analytical approaches are necessary.
App Note / Case Study
Protein Sequence Analysis: Next-Generation vs Mass Spectrometry Methods
Mass spectrometry is regarded as the gold standard for protein identification; however, this technique cannot easily discriminate between protein variants and is not accessible to everyday scientists due to the high cost, space and expertise required.
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