A Novel Perfusion Technique for Multiomics Studies on Hepatocyte Aging

The liver is a very good example of how tissue architecture can influence aging. Composed mainly of hepatocytes, the position of these cells is key to their role and determines changes in their metabolism and aging profile.

Researchers from the Max Planck Institute have conducted an in-depth multiomics analysis of functional and healthy hepatocytes, characterizing transcriptional, epigenetic, lipidomic and functional signatures to understand the effects of aging.

In this webinar, you’ll hear all about their research, including the novel perfusion technology for resected mouse liver that makes it easy and convenient to obtain viable hepatocytes to analyze.

Attend this webinar to:

• Get a glimpse of the throughput, yield and viability of the obtained hepatocytes after a short and easy to follow protocol
• Learn how isolated hepatocytes were thoroughly characterized by different transcriptomics and epigenomics techniques to gain an in-depth understanding of their aging profile
• Understand how the architecture of organs, in this case of the liver, can greatly influence the aging trajectory of cells