Latest Posters
Poster
Histone Deacetylase 6 (HDAC6) As A Therapeutic Target in Chronic Lymphocytic Leukemia
This study investigates the role of histone deacetylase 6 (HDAC6) in chronic lymphocytic leukemia and establishes it as a novel therapeutic target for the treatment of this disease.
Poster
Inhibition of The Auto-inflammation Suppressor Protein ISG15 Triggers Preeclampsia by Blocking Trophoblast Migration and Invasion
In summary, ISG15 expression levels are crucial for trophoblast morphology and function (migration/invasion). By blocking trophoblast invasion, reduced ISG15 levels could contribute to impaired spiral artery transformation that reduces utero-placental blood flow in preeclampsia. Thus, agents inducing ISG15 expression are likely to be therapeutic in preeclampsia.
Poster
An Emerging Phenotype of Partial RAG 1/2 Deficiency Among Young Children with Autoimmunity and Viral Infections
We describe the natural history of a cohort of 12 patients with confirmed partial RAG1/2 mutations and autoimmunity at a young age. We were seeking the link between viral infections and autoimmunity and tested candidate biomarkers that may reflect the underlying RAG1/2 protein deficiency.
Poster
Complete alignment identification of CRISPR-Cas9 genomic off-targets using Edit-R CRISPR specificity tool and a comprehensive analysis of positional mismatch tolerance
A web tool that performs complete crRNA specificity checking is introduced. In addition, we evaluated positional off-targeting of the CRISPR system.
Poster
MicroRNAs as Bile-Based Biomarkers in Pancreatic Cancer and Biliary Tract Cancers
In this study, the role of miRNAs has been assessed in a large cohort of pancreatic cancer.
Poster
Is Oxford Nanopore Technology Ready for Clinical Diagnostics?
Our objective is to validate diagnostic services using Oxford Nanopore’s Minion in the first instance and to evaluate the cost and performance compared to existing sequencing technology in areas such as tumour DNA sequencing (and circulating tumour DNA), virology, microbiology, genetics and HLA-typing.
Poster
Determination of the Fat Content Profile of different Chocolate Products using an Automated Workflow for the Generation of Fatty Acid Methyl Esters (FAME)
The method allows for automated determination of total fat content and quantitative analysis of saturated and unsaturated cis- and trans- fatty acids of different chocolate products.
Poster
Performance of the D5000 and High Sensitivity D5000 ScreenTape Assays for the 4200 TapeStation System
Here, we focus on quantification, sizing, and sensitivity of both D5000 ScreenTape assays.
Poster
Designing highly functional and specific guide RNAs for knockout and achieving precise knockin using the homology-directed repair pathway
We aim to better understand the parameters affecting CRISPR-Cas9 editing efficiency for functional gene knockout utilized synthetic crRNAs and tracrRNA.
Poster
What Are You Eating? An Analysis of Dietary Intake Measures Among College Students
To better understand the dietary practices of emerging adults, and college students more specifically, it is necessary to use effective measurement techniques. The purpose of this critique is to compare dietary intake measures used in research assessing dietary practices among college students.
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