Latest Posters
Poster
Inhibiting CK2α from Outside the Active Site
Here we report the creation and characterization of a unique inhibitor of CK2a that targets a novel cryptic pocket and was developed using fragment-based methods.
Poster
The Impact of MRI on Genitourinary and Gastrointestinal Toxicity after Radiation Therapy
MRI has several advantages relative to other imaging modalities in evaluating, diagnosing, and planning treatment for prostate cancer. However, it is rarely ordered for localized disease. While the diagnostic abilities have been studied, little has been done to associate clinical outcomes with prostate cancer patients who received MRI.
Poster
Change in pattern of secondary malignancies following Kaposi's sarcoma in the era of anti-retroviral therapy
This study hypothesis is that the secondary cancers that develop in patients with KS have changed.
Poster
Pharmacological Ascorbic Acid and Hyperbaric Oxygen Therapy Target Tumor Cell Metabolism via an Oxidative Stress Mechanism
This data indicates that AA exhibits anti-cancer effects in vitro through an OxS mechanism and that HBOT can enhance this therapeutic effect.
Poster
An Antitumor Antibody Response to Attenuate Metastatic Melanoma in a Murine Model
These preliminary results show antitumor activity of adoptive cell transfer of MHC class mismatched CD4(+) T-cells. The finding of reduced numbers of pulmonary metastases correlates with increased serum anti-OVA IgG and increased germinal center development in the spleen.
Poster
Activation of PTEN lipid phosphatase function in lung cancer
We have discovered novel small molecule compounds that directly induce PTEN function and antagonize PI3K/AKT pathway activity in lung cancer cells.
Poster
Isolated Limb Infusion as a Limb Salvage Strategy for Locally Advanced Extremity Sarcoma
We review perioperative and oncological outcomes and compare survival between ILI and amputation.
Poster
Comparison of the Biological Effects of Long-Term Exposure of Human Bronchial Epithelial Cells to Total Particulate Matter from 3R4F Cigarette Smoke or Aerosol from the Candidate Modified Risk Tobacco Product (cMRTP) THS2.2
We mimicked chronic exposure in smokers’ airways by continuously exposing BEAS-2B cells to TPM from 3R4F cigarette smoke or aerosol of the Tobacco Heating System 2.2 (THS2.2), a cMRTP, for 12 weeks.
Poster
Quantitative Cell-based Bioassays for Individual and Combination Immune Checkpoint Immunotherapy Targets
The human immune system is comprised of a complex network of immune checkpoint receptors that are promising new immunotherapy targets for the treatment of a variety of diseases including cancer and autoimmune-mediated disorders.
Poster
Inecalcitol Stimulates CD38 Expression in Multiple Myeloma and Acute Myeloid Leukemia Cell Lines
Inecalcitol is a vitamin D receptor agonist currently in Phase II clinical trial in AML (acute myeloid leukemia). Inecalcitol increases the expression of CD38 at the surface of 5 multiple myeloma cell lines; therefore, inecalcitol could potentiate the clinical response of MM patients to a therapeutic anti-CD38 antibody
Inecalcitol induces the expression of the CD38 antigen at the surface of 4 AML cell lines; thus, inecalcitol could render AML patients sensitive to a therapeutic anti-CD38.
Inecalcitol induces the expression of the CD38 antigen at the surface of 4 AML cell lines; thus, inecalcitol could render AML patients sensitive to a therapeutic anti-CD38.
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