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Cancer genomes are the result of diverse mutation processes that have often accumulated over decades. Scientists have analyzed the molecular evolution of tumors after exposure to mutagenic chemicals.

The reason why targeted treatment for non-small cell lung cancer fails to work for some patients, particularly those who have never smoked, has been discovered by researchers from UCL, the Francis Crick Institute and AstraZeneca.

New research illustrates that the risk of secondary cancers following CAR T-cell therapy is low.

Researchers have analyzed how an antidiabetic treatment could help control the growth of tumors, potentially paving the way for the design of better cancer treatments.

For nearly two decades, how kidney cancer becomes resistant to rapalog drugs has baffled the scientific community. Now a study by researchers at UT Southwestern Medical Center’s Kidney Cancer Program sheds light

While most cell types experience a functional decline after years of proliferation and replication, T cells can proliferate seemingly indefinitely.

Immune system cells called macrophages play an unexpected role in the complicated connection between obesity and cancer, a Vanderbilt University Medical Center-led research team has discovered.

T-cell stimulating biomaterial that slowly biodegrades under the skin stimulates CAR-T cells in the body to improve therapeutic efficacy in an aggressive mouse tumor model.

A computer program based on data from nearly a half-million tissue images and powered by artificial intelligence can accurately diagnose cases of adenocarcinoma.

Investigators have identified a gene whose expression confers a growth advantage to metastatic cancer cells, which cause 90% of cancer-related deaths. Silencing this gene in lab models of cancer prevented metastatic cells from growing and spreading.