Latest App Notes & Case Studies

In the quest for therapeutic or analytical antibodies, it is crucial to carefully select antibodies based on their kinetics, affinity, specificity and biophysical attributes. Antibody screening plays a pivotal role in identifying cell clones that generate antibodies suited to a specific purpose, often challenging these antibodies with a known antigen.

This application note highlights how combined machine learning and FTIR technology can enhance the overall efficiency of your analytical workflow.

Immunogenicity is a key consideration in the development of safe gene therapy products. In fact, certain product components can cause unintended immune responses with life-threatening implications if not addressed.

Monoclonal antibody (mAb)–based therapeutics have been very successful in treating various diseases, including cancer. The manufacturing of these therapeutic antibodies is a complex operation with low levels of aggregates being a critical quality attribute of the final product, as this will impact the biological activity.

When planning for your sample storage needs, there’s no doubt you’ve discovered the many types of freezers on the market—upright, under-counter, side-by-side, and chest, to name a few. So, what advantages do chest freezers have over other types of freezers?

In the field of protein therapeutics, a protein-polymer conjugation strategy can improve the protein’s clinical potential by overcoming some of the challenges, such as physiochemical instability, immunogenicity and suboptimal circulation half-life.

In this app note, learn more about the advantages of batch centrifugation and how you can optimize downstream processing of primary T cells, and share some exemplary results for viability and recovery of T cells after washing and concentration.

This application note outlines the importance of reagent consistency in organoid tissue culture.

This application note demonstrates how reliable kinetics and affinity can be obtained from single measurement data, increasing sample throughput and saving sample material.

Adeno-associated virus (AAV) technology has become a crucial method for delivering gene therapy drugs and vaccines. The quantitation of viral capsids enables researchers to ensure that AAV preparations are of high quality and potency. However, challenges remain with the accurate quantitation and detection of multiple AAV serotypes.