Latest App Notes & Case Studies

Download this app note to discover a method of recombinant protein expression that enables correct protein folding and post translational modification, is suitable for high-density cell culture, and can produce both secreted and intracellular proteins of various species.

Find out how scientists determined which of five extraction methods was optimal for use in a long-read sequencing workflow by comparing the sample quality, sample size and sequencing results.

This tech note highlights technology that switches easily between DNA and RNA analysis to ensure quick and reliable quality checks and precise sizing of DNA and IVT RNA products.

Single cell and spatial technologies that profile gene expression across whole tissues are revolutionizing the resolution of molecular states in clinical tissue samples.

Data silos, lack of interoperability and the preservation of patient privacy all present challenges to the global sharing of genomic data.

Many downstream experiments in molecular biology, such as next-generation sequencing, depend on the use of reasonably pure nucleic acid samples in adequate concentration ranges.

One approach to develop drugs for infectious diseases involves a comprehensive understanding of human-pathogen protein interactions, as targeting host proteins helps reduce the possibility of drug resistance by creating a more significant evolutionary barrier for the virus.

Using genome-wide CRISPR knockout screens, followed by focused CRISPR screens, researchers at Boehringer Ingelheim probed the gene-phenotype relationship of human monocyte phagocytosis when the cells were challenged with Staphylococcus aureus.

Download this article to learn about a next-generation sequencing technology that integrates genetic and biochemical testing as well as can efficiently diagnose more than 180 metabolic diseases.

Because of this, plasmids ideally suit experimental protocols that include cloning. Inserting a piece of DNA into the linearized plasmid and generating multiple copies of the plasmid allows scientists to study DNA sequences or genes.