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Advancing Gentler Cell Therapies for Blood Cancer
Researchers have developed an approach to “deleting” a blood system affected by leukemia while simultaneously building up a new, healthy system with donor blood stem cells.

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HIV Vaccine Candidate Induces Broadly Neutralizing Antibodies in Humans
A trial HIV vaccine has triggered low levels of HIV bnAbs in humans. The findings provide proof that a vaccine can elicit bnAbs to fight diverse strains of HIV and that it can initiate the process within weeks after just two immunizations.

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COVID-19 Re-Vaccinations Elicit Neutralizing Antibodies Against Future Variants
Re-vaccination against SARS-CoV-2 promotes the development of broadly inhibitory antibodies against a wide range of variants, which supports the use of yearly booster vaccines.

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Unique CRISPR-Cas System Shows Promise in Fight Against Antimicrobial Resistance
In nature, bacteria use CRISPR-Cas systems to fight off deadly viruses. A recent international collaboration has shed light on the most enigmatic CRISPR-Cas systems; the type IV system.

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Gene Delivery Vehicle Shows Promise for Human Gene Therapy
Scientists have engineered an adeno-associated virus (AAV) that efficiently crosses the blood-brain barrier in human cell models and delivers genes throughout the brain in humanized mice.

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Novel Gene Therapy Targets Disc-Related Back Pain
An estimated 40% of low-back pain cases are attributed to degeneration of the cushiony intervertebral discs that absorb shocks and provide flexibility to the spine.

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HPV Vaccination Program in England Effectively Reduces Cervical Disease in All Socioeconomic Groups
Routine vaccination of young people against HPV in the UK has reduced the incidence of cervical disease across socioeconomic groups.

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Immunotherapy Could Be Used To Boost the Immune System of Older Individuals
Immunotherapy could be used to enhance immune responses in older people, making them less vulnerable to infections, reports a new study.

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Semaglutide Could Offer Long-Term Weight Loss and Cardiovascular Protection Effects
In the longest clinical trial yet of semaglutide, a prescription drug sold under the brand names Wegovy and Ozempic, researchers analyzed the drug's long-term weight loss effects.

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Synthetic Molecule Mimics Anti-Clotting Effects of Blood-Sucking Critters
Nature gave ticks, mosquitos and leaches a quick-acting way to keep blood from clotting while they extract their meal from a host. Now the key to that method has been harnessed as a potential anti-clotting agent.
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