Latest App Notes & Case Studies
App Note / Case Study
High-Resolution mRNA Poly(A) Tail Analysis With CGE-UV
This application note describes how capillary gel electrophoresis with UV detection (CGE-UV) can attain single-nucleotide resolution over a broad size range, making it suitable for the development of QC assays.
App Note / Case Study
Large-Scale Expansion of PSCs To Support Cell Therapy Manufacturing
This application note introduces a suspension medium for use in the production of pluripotent stem cells (PSCs) for allogeneic therapies, enabling a seamless transition from research to clinical settings.
App Note / Case Study
Biologics Developability: Optimization of Engineered mAbs With Multi-Parameter Stability Characterization
The biologic drug development process is expensive and often leads to time and money lost on candidates that never reach the clinic. Improved developability profiles enable researchers in the early discovery stages to select candidates that have a great chance at clinical success.
App Note / Case Study
Optimized Analysis of Semi-Volatile Organic Compounds
This app note explores the latest quadrupole gas chromatography mass spectrometry (GC-MS) system which can fulfill EPA analytical criteria and features an innovative detector system providing enhanced performance.
App Note / Case Study
Explore High-Quality Automated Electrophoresis for Protein Analysis
This tech note explores how automated CE-SDS provides rapid, precise and accurate quantification of proteins and impurities.
App Note / Case Study
Single-Use Technology Designed for Small Batches in Gene Therapy Manufacturing
But how do you purify small volumes for preclinical and clinical studies without losing too much to processing or leaving capacity unused?
App Note / Case Study
Screen Single Cells in Their Own Microenvironment
This app note highlights a uniquely protective environment to support cell viability and integrity during incubation and shield cells against shear stress during subsequent analysis.
App Note / Case Study
Viral Clearance in a Downstream AAV Process
This application note shows how chromatographic modes of separation can achieve the necessary levels of virus removal while preserving the integrity of the AAV product.
App Note / Case Study
The Latest Advancements in Automated Confocal Imaging
By collecting more light and better correcting for light distortion, water immersion capabilities can unlock advanced imaging potential for greater insight into cellular pathways and processes.
App Note / Case Study
Achieve Sensitive Quantitation of GLP Analogs in Biological Matrices
Glucagon-like peptide-1 (GLP-1) analogs regulate systemic homeostasis, making them effective in the treatment of type 2 diabetes. However, their low bioavailability limits their detection and quantitation in biological matrices, causing challenges in drug development.
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