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Latest App Notes & Case Studies

mRNA Strand
App Note / Case Study

High-Resolution mRNA Poly(A) Tail Analysis With CGE-UV

This application note describes how capillary gel electrophoresis with UV detection (CGE-UV) can attain single-nucleotide resolution over a broad size range, making it suitable for the development of QC assays.
Cell Structure
App Note / Case Study

Large-Scale Expansion of PSCs To Support Cell Therapy Manufacturing

This application note introduces a suspension medium for use in the production of pluripotent stem cells (PSCs) for allogeneic therapies, enabling a seamless transition from research to clinical settings.
engineered stable mAbs
App Note / Case Study

Biologics Developability: Optimization of Engineered mAbs With Multi-Parameter Stability Characterization

The biologic drug development process is expensive and often leads to time and money lost on candidates that never reach the clinic. Improved developability profiles enable researchers in the early discovery stages to select candidates that have a great chance at clinical success.
Volatile Organic Compounds
App Note / Case Study

Optimized Analysis of Semi-Volatile Organic Compounds

This app note explores the latest quadrupole gas chromatography mass spectrometry (GC-MS) system which can fulfill EPA analytical criteria and features an innovative detector system providing enhanced performance.
Protein Analysis
App Note / Case Study

Explore High-Quality Automated Electrophoresis for Protein Analysis

This tech note explores how automated CE-SDS provides rapid, precise and accurate quantification of proteins and impurities.
AKTA System
App Note / Case Study

Single-Use Technology Designed for Small Batches in Gene Therapy Manufacturing

But how do you purify small volumes for preclinical and clinical studies without losing too much to processing or leaving capacity unused?
Screen Single Cells in Their Own Microenvironment
App Note / Case Study

Screen Single Cells in Their Own Microenvironment

This app note highlights a uniquely protective environment to support cell viability and integrity during incubation and shield cells against shear stress during subsequent analysis.

Vaccine Vials
App Note / Case Study

Viral Clearance in a Downstream AAV Process

This application note shows how chromatographic modes of separation can achieve the necessary levels of virus removal while preserving the integrity of the AAV product.
The Latest Advancements in Automated Confocal Imaging
App Note / Case Study

The Latest Advancements in Automated Confocal Imaging

By collecting more light and better correcting for light distortion, water immersion capabilities can unlock advanced imaging potential for greater insight into cellular pathways and processes.

Glycagon
App Note / Case Study

Achieve Sensitive Quantitation of GLP Analogs in Biological Matrices

Glucagon-like peptide-1 (GLP-1) analogs regulate systemic homeostasis, making them effective in the treatment of type 2 diabetes. However, their low bioavailability limits their detection and quantitation in biological matrices, causing challenges in drug development.
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