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Traditionally, there has been a compromise between performance and sustainability.

The NovaSeq X Plus system enables sequencing of >20,000 genomes per year and delivers data in half the time with a 2.5x improvement in throughput. Breakthrough advancement in chemistry, optics and software contribute to fast, highly accurate and cost-effective data.

Researchers looking to answer complex biological questions often require increased statistical power, larger studies and deeper sequencing methods.

The hypothalamic-pituitary-thyroid axis (HPT axis) is conserved across vertebrate evolution. Perturbation of thyroid hormone homeostasis (THH) can lead to adverse effects in thyroid function affecting growth, metabolism and cognitive function.

The growing use of RNA-based vaccines and therapies has focused much attention and effort on developing conditions for maximizing the yield and efficiency of the in vitro transcription (IVT) reactions used to produce mRNA. IVT procedures involve the biosynthesis of RNA from a linear DNA template containing an appropriate transcription promoter. But how do different buffer conditions and nucleotide concentrations impact the IVT reaction?

Membrane proteins are a notoriously difficult class of proteins to express, purify and characterize. Expression levels of membrane proteins in mammalian expression systems, the preferred system to generate native-like post-translational modifications, are often so low that yields are unsuitable for the intended downstream uses.

Nucleic acid amplification and detection techniques are highly valuable tools that can be used across a wide range of applications... Real-time PCR, also known as quantitative PCR (qPCR), is the gold-standard for sensitive, specific detection and quantification of nucleic acid targets.

Cells establish their function, identity and state through the careful orchestration of complex molecular mechanisms leading to gene expression. To characterize cells more accurately, it is important to evaluate gene expression at both transcript and protein levels.

Download this poster to learn more about unbiased spatial gene expression,
application of spatial gene expression plus immunofluorescence validation and targeted analysis.

The diversity of potential mRNA-based therapies has led to increased interest in using synthetic mRNA as a tool in the treatment of multiple diseases. Nevertheless, obtaining larger quantities of synthetic mRNA for clinical treatment remains a challenge.

Laboratory automation has become ubiquitous in many pharmaceutical and biotechnology laboratories and supports a wide range of applications including drug discovery and development, synthetic biology, food and animal health, clinical diagnostics and many others.